Vitamin D and polycystic ovary syndrome: an integrating review

  • Ione Maria Ribeiro Soares Lopes
  • Caroliny Gonçalves Rodrigues Meireles Universidade Federal do Piauí
  • Iarlla Silva Ferreira
  • Nadya dos Santos Moura
  • Francisca Diana da Silva Negreiros
  • Alice Maria Correia Pequeno


Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrinopathyin women of reproductive age. It causes a metabolic syndrome characterized by insulin resistance, hyperinsulinemia, and dyslipidemia. Vitamin D deficiency and its association with PCOS still represents a controversial subject in the literature.

Objective: In this context, this study aimed to understand the association between polycystic ovary syndrome and vitamin D deficiency, and how it occurs.

Method: It was an integrative review conducted in the PubMed, Scopus, LILACS, and CINAHL databases from August 2016 to January 2017, with a sample of 7 articles analyzed in their entirety.

Results: The evidences according to the studies conducted and the conclusions they identified. 

Conclusions: It was concluded that we cannot yet assume that vitamin D deficiency contributes to the pathogenesis of PCOS, nor that the syndrome causes vitamin D deficiency, since the studies are controversial and there is a need for research with higher levels of evidence to clarify these doubts.

Apr 19, 2017
How to Cite
LOPES, Ione Maria Ribeiro Soares et al. Vitamin D and polycystic ovary syndrome: an integrating review. International Archives of Medicine, [S.l.], v. 10, apr. 2017. ISSN 1755-7682. Available at: <>. Date accessed: 27 may 2017. doi:
Obstetrics & Gynecology