Breast Cancer as a late complication of treatment for lymphoma in children and adolescents

  • Antonio Marlos Duarte de Melo
  • Jose Angelo Araújo Sampaio
  • Ricardo Souto Quidute

Abstract

The treatment for pediatric patients affected by Hodgkin's lymphoma, including chemotherapy and radiotherapy, has offered a high survival rate, but may be responsible for the appearing of breast cancer in later form in these same people. The 20-year survival rate can reach 90% of patients suffering from Hodgkin's disease, but they may suffer sequelae, among which malignant secondary neoplasms, including breast cancer. Most studies show that the malignancy of breast tissue is the main secondary sequel to radiotherapeutics’ treatment for patients with Hodgkin's lymphoma in childhood.


 


Keywords: Breast Cancer; Hodgkin's Lymphoma; Radiotherapy.

References

1- Schellong G, Riepenhausen M, Ehlert K et al. Breast Cancer in Young Women After Treatment for Hodgkin’s Disease During Childhood or Adolescence. Dtsch Arztebl Int. 2014 Jan 6; 111(1-2): 3-9.

2- Dörffel W, Riepenhausen M, Lüders H et al. Secondary Malignancies Following Treatment for Hodgkin’s Lymphoma in Childhood and Adolescence. Dtsch Arztebl Int. 2015 Mai 1; 112(18): 320-327.

3- Candela JL. CE: Cardiotoxicity and Breast Cancer as Late Effects of Pediatric and Adolescent Hodgkin Lymphoma Treatment. Am J Nurs. 2016 Apr;116(4):32-42.

4- Green DM, Hyland A, Barcos MP et al. Second malignant neoplasms after treatment for Hodgkin's disease in childhood or adolescence. J Clin Oncol. 2000 Apr;18(7):1492-9.

5 - Von der Weid NX. Adult life after surviving lymphoma in childhood. Support Care Cancer. 2008 Apr;16(4):339-45.
6 - Beaty O 3rd, Hudson MM, Greenwald C et al. Subsequent malignancies in children and adolescents after treatment for Hodgkin's disease. J Clin Oncol. 1995 Mar; 13(3): 603-9.
Published
2017-04-26
How to Cite
DE MELO, Antonio Marlos Duarte; SAMPAIO, Jose Angelo Araújo; QUIDUTE, Ricardo Souto. Breast Cancer as a late complication of treatment for lymphoma in children and adolescents. International Archives of Medicine, [S.l.], v. 10, apr. 2017. ISSN 1755-7682. Available at: <http://imedicalsociety.org/ojs/index.php/iam/article/view/2549>. Date accessed: 23 aug. 2017. doi: https://doi.org/10.3823/2426.
Section
Pediatric Oncology