Seminal Ferritin And Seminal Parameters In Patients Undergoing Chronic Hemodialysis
Background: to verify the association of seminal parameter (SP) and seminal ferritin(SF) levels in patients undergoing chronic hemodialysis (CH), admitting possible antioxidative activity of SF.
Methods: this was a case-control study in group of 60 men (case) in CH with more than 6 months and group of healthy men(control), aged 18-60 years, without clinical or laboratory signs of infection / inflammation. Patients underwent semen analysis, fertility index(FI) calculation, measurement of SF and hormonal profile(follicle-stimulating hormone, luteinizing hormone, total testosterone, and prolactin levels).
Results: There were significant differences between cases and control (Table 1) in SP(p = 0.000), sex hormones (p = 0.000) and FI [0, 85(0,57) vs 5,54(1,3), p=0,000]. There was no difference between cases and control(Table 1) in SF levels (226.45 ± 51.03 vs 241.52 ± 30.52, p = 0.137) and age(49,47 ±5,56 vs 47,90 ± 6,22, p=0,229).There was no correlation (Table 2) between SF and FI(r = 0.049, p = 0.711) and SP(p> 0.05).
Conclusion: the results suggest that SF is not associated with changes in seminal parameters in patients undergoing chronic hemodialysis, and is not useful singly for initial evaluation of seminal parameters.
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