Transverse myelitis associated with Zika virus infection: a Case Report
Title: Transverse myelitis associated with Zika virus infection: a Case Report.: The zika virus belongs to the family flaviviridae, and is transmitted by the arthropod Aedes aegypt. Its major importance is related to the several debilitating neurological manifestations associated with it, such as transverse myelitis.
Case: The authors report a case of transverse myelitis in a patient with a previous diagnosis of Zika virus infection. After the image exams and serology, the diagnosis was confirmed and treatment with prednisone was performed with an unsatisfactory clinical outcome.
Conclusion: Brazil is the country of greatest concern worldwide due to the thousands of Zika cases with associated neurological complications, causing sequels and physical disabilities. However, cases worldwide have increased substantially.
2. Roos RP. Zika Virus—A Public Health Emergency of International Concern. JAMA Neurol. 2016;73(12):1395-1396. doi:10.1001/jamaneurol.2016.3677
3. Melo ASDO, Aguiar RS, Amorim MMR, Arruda MB, Melo FDO, Ribeiro STC, Batista AGM, Ferreira T, dos Santos MP, Sampaio VV, Moura SRM, Rabello LP, Gonzaga CE, Malinger G, Ximenes R, de Oliveira-Szejnfeld PS, Tovar-Moll F, Chimelli L, Silveira PP, Delvechio R, Higa L, Campanati L, Nogueira RMR, Filippis AMB, Szejnfeld J, Voloch CM, Ferreira OC, Brindeiro RM, Tanuri A. Congenital Zika Virus InfectionBeyond Neonatal Microcephaly. JAMA Neurol. 2016;73(12):1407-1416. doi:10.1001/jamaneurol.2016.3720
4. World Health Organization. WHO director-general briefs executive board on Zika situation. http://www.who.int/dg/speeches/2016/zika-situation/en/. Accessed July 1, 2016.
5. BOLETIM EPIDEMIOLÓGICO - Volume 46 - nº 03 - 2015 - Monitoramento dos casos de dengue, febre de chikungunya e febre pelo vírus Zika até a Semana Epidemiológica 53, 2014. Secretaria de Vigilância em Saúde- Ministério da Saúde. Disponível em:
6. Vasconcelos PFC. Doença pelo vírus Zika: um novo problema emergente nas Américas?. Rev Pan-Amaz Saude [Internet].2015 June; 6( 2 ): 9-10.
7. Calvet G, Aguiar RS, Melo AS, et al. Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis. 2016;16(6):653-660.
8. Mécharles S, Herrmann C, Poullain P, et al. Acute myelitis due to Zika virus infection. Lancet. 2016;387(10026):1481.
9. Cao-Lormeau V, Blake A, Mons S, et al. Guillain-Barré syndrome outbreak caused by Zika virus infection in French Polynesia [published online February 29, 2016]. Lancet. doi:10.1016/S0140-6736(16)00562-6
10. Juan-Manuel Anaya, Yhojan Rodríguez, Diana M. Monsalve, Daniel Vega, Ernesto Ojeda, Diana González-Bravo, Mónica Rodríguez-Jiménez, Carlos A. Pinto-Díaz, Pablo Chaparro, María L. Gunturiz, Aftab A. Ansari, M. Eric Gershwin, Nicolás Molano-González, Carolina Ramírez-Santana, Yeny Acosta-Ampudia, A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia, Journal of Autoimmunity, Volume 77, February 2017, Pages 123-138, ISSN 0896-8411,
11. Dirlikov E, Major CG, Mayshack M, Medina N, Matos D, Ryff KR, et al. Guillain-Barré syndrome during ongoing Zika vírus transmission—Puerto Rico, January 1–July 31, 2016. MMWR\ Morb Mortal Wkly Rep. 2016;65:910–4. Recent prospective Zika virus-Guillain Barré syndrome surveillance system from Puerto Rico.
12. Pinheiro Talys J., Guimarães Luis F., Silva Marcus Tulius T., Soares Cristiane N.. Neurological manifestations of Chikungunya and Zika infections. Arq. Neuro-Psiquiatr. [Internet]. 2016 Nov [cited 2017 Dec 04] ; 74( 11 ): 937-943. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001100937&lng=en. http://dx.doi.org/10.1590/0004-282x20160138.
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