The current profile of the patient with atrial fibrillation
Abstract: Atrial fibrillation (AF) is the most common supraventricular arrhythmia, characterized by an irregular and extremely rapid atrial electrical activation that causes loss of atrial mechanical function and important hemodynamic consequences. AF classification is important in both the therapeutic approach and the prognosis. Several classifications based on the ECG patch, epicardial or endocavitary records have been performed over time, but no classification can take into account all the characteristics of AF and especially associated diseases, which may be both the cause and consequence of arrhythmia. Aim: The aim of the study is to establish the current profile of the patient with atrial fibrillation in the new era of oral anticoagulant therapy and sinus rhythm restoration.
Material and methods: The trial was conducted on patients with atrial fibrillation hospitalized between 01.10.2014-31.03.2015 at Institute of Cardiovascular Diseases ”Prof. Dr. G. Georgescu”, Iasi. Patients included in the study were analyzed according to age and sex, criteria for the clinical and paraclinic definition for atrial fibrillation.
Results: Atrial fibrillation is an extremely common cardiovascular pathology and is present in about one-third of patients admitted to our clinic. Cardiovascular diseases such as hypertension, ischemic coronary artery disease, and valvulopathy are common in patients with AF. Patients with AF are usually elderly patients with many associated diseases in whom sinus rhythm restoration treatment and anticoagulant therapy are difficult to establish. AF is one of the most common arrhythmias that complicates the evolution of acute myocardial infarction, association between dual antiplatelet therapy and anticoagulation treatment, increasing the risk of bleeding complications.
Conclusions: Atrial fibrillation is an extremely common cardiovascular pathology and is present in about one-third of patients admitted to our hospital. The data obtained revealed that this arrhythmia occurs in a small number of cases as the only pathology of the patient, usually associated with numerous comorbidities. Cardiovascular diseases such as hypertension, ischemic coronary artery disease, valvulopathy are common in our practice. Patient with AF is a patient who requires long-term anticoagulant therapy and in whom sinus rhythm recovery therapy is dependent on the precocity of presentation to the physician, as well as on the therapeutic resources of current medicine.
2. The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Guidelines for the management of atrial ﬁbrillation. Eur Heart J. 2016; 37: 2893–962.
3. Zoni-Berisso M, Lercari F, Carazza T, Domenicucci S. Epidemiology of atrial fibrillation: European perspective. Clinical Epidemiology. 2014; 6: 213-20.
4. Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, et al. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation. 2014; 129(8):837-47.
5. Santosh Rane, Kristen K. Patton. Impact of Sex and Ethnicity on Arrhythmic Risk. Curr Cardiol Rep. 2015; 17: 50.
6. Schmitt J, Duray G, Gersh BJ, Hohnloser SH. Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications. Eur Heart J. 2009; 30 (7):1038–45.
7. Violi F, Soliman EZ, Pignatelli P, Pastori D. Atrial Fibrillation and Myocardial Infarction: A Systematic Review and Appraisal of Pathophysiologic Mechanisms. J Am Heart Assoc. 2016; 20 (5):1-13.
8. Pedersen OD, Bagger H, Køber L, Torp-Pedersen C. The occurrence and prognostic significance of atrial fibrillation/-flutter following acute myocardial infarction. Eur Heart J. 1999; 20 (7):748–54.
9.Vlachos K, Letsas KP, Korantzopoulos P, Liu T, Georgopoulos S, Bakalakos A, et al. Prediction of atrial fibrillation development and progression: current perspectives. World J Cardiol. 2016; 8(3):267-76.
10. Widgren V, Dencker M, Juhlin T, Platonov P, Willenheimer R. Aortic stenosis and mitral regurgitation as predictors of atrial fibrillation during 11 years of follow-up. BMC Cardiovasc Disorders. 2012; 12:92.
11. Pamukcu B, Bitigen A. Mitral Regurgitation and Atrial Fibrillation: The Contribution of Impaired Left Atrial Appendage Function to Atrial Thrombogenesis. Atrial Fibrillation - Basic Research and Clinical Applications. Ed. Jong-II Choi. 2012; 414: 373-80.
12. Cagdas M, Velibey Y, Guvenc TS, Gungor B, Guzelburc O, Calik N et al. Evaluation of atrial electromechanical conduction delay in case of hemodynamically insignificant rheumatic heart disease: A tissue Doppler study. Cardiology Journal. 2015; 22 (6): 683–90.
13. Dzeshka MS, Shantsila A, Shantsila E, Lip GY. Atrial Fibrillation and Hypertension. Hypertension. 2017;70:854-61.
14. Alves-Cabratosa L, García-Gil M, Comas-Cufí M, Ponjoan A, Martí R, Parramon D et al. Incident Atrial Fibrillation Hazard in Hypertensive Population A Risk Function From and For Clinical Practice. Hypertension. 2015; 65:1180-1186.
15. Andrade J, Khairy P, Dobrev D, Nattel S. The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circ Res. 2014; 114(9):1453-68.
16. Colilla S, Crow A, Petkun W, Singer DE, Simon T, Liu X. Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population. Am J Cardiol. 2013; 112(8):1142-7.
17. Petrovich Zaretskiy A, Valerievich Ilyin A, Pavlovich Kuleshov A, Valerievna Poteryakhina A, Valerievich Poteryakhin A. Features of Analysis and Daily Registration of ECG in Patients with Paroxysmal Atrial Fibrillation. Biol Med (Aligarh). 2015; 7 (2): 1-4.
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