Carolina Cord Blood Bank

Carolina Cord Blood Bank

This article is about Carolina Cord Blood Bank, a public bankOpens in a new tab.. If you are looking for reviews of private banksOpens in a new tab., you will find them in this article, together with advices about how to identify the best cord blood bankOpens in a new tab. for you and your baby.

Expectant parents have an option to store umbilical cord bloodOpens in a new tab. after the delivery for future medical use.  The initial dilemma after the decision to store cord bloodOpens in a new tab. is whether to donate the bloodOpens in a new tab. in some of the public banking facilitiesOpens in a new tab. or to store the umbilical cord bloodOpens in a new tab. for private use within the familyOpens in a new tab..  There has been a lot of debate in the scientific and expert community regarding the ethical issues surrounding banking of stem cellsOpens in a new tab..  Actually, the foundation of both publicOpens in a new tab. and private banking systemsOpens in a new tab. raised plenty of medical, social, ethical and legal issues.  The main issue that most of the experts find controversial is the usability of privately banked cord blood unitsOpens in a new tab..


Some think that families at a low risk of the development of a disease manageable by stem cell transplantation would not benefit from private banking of cord bloodOpens in a new tab..  Alternatively, these stem cells may be beneficial to other families at the need of transplantation.  However, there are no ethical obstacles if the parents finally choose to store cord blood for private use.Opens in a new tab.  In any case, availability of stem cells for transplantation or research purposes should not be a privilege but a fundamental right for all.

Public Cord Blood Banking and Carolina

The success of initial transplantations of umbilical cord blood led the experts to investigate and find solutions for storage of cord blood unitsOpens in a new tab. in order to facilitate the process of obtaining a compatible cord blood units.  Creating the first cord blood banks was a complex and sophisticated process requiring knowledge on how to successfully collect,Opens in a new tab. transport, store and release cord blood units for cell-based treatment.  The first cord blood banksOpens in a new tab. were public and contained cord blood units intended for transplantation to both an unrelated and related recipients.  The rapid development of public banking systemsOpens in a new tab. leads to the foundation of 54 public cord blood banks that released approximately 10000 of cord blood units for treatment purposes.

Another benefit of public banking facilitiesOpens in a new tab. includes the possibility that the samples of insufficient quality may be used for research and development of new therapeutic modalities in the field of regenerative medicine.  In order to improve the process and facilitate the search of a compatible stem cell unit, public cord banksOpens in a new tab. developed a specific electronic sharing system that serves as a unique registry of cord blood units for multiple banking facilities.

Carolina Cord Blood Bank Facts

Carolina Cord Blood Bank is actively supported by several most prominent health institutions including the National Institute of Health, American Red Cross, the National Marrow Donor Program and other.  Founded back in 1998, Carolina Cord Blood Bank represents one of the most experienced cord blood banking systems.  Carolina Cord Blood Bank is also one of the largest public cord blood banksOpens in a new tab. in the world and represents a section of the Duke University School of Medicine.

Carolina Cord Blood Bank is a banking system that stores most diverse cord blood units, meaning that search for a compatible donor should not represent an issue.  Tens of thousands of families having a diverse ethnic and racial origin have donated cord bloodOpens in a new tab. with Carolina Cord Blood Bank.  This is extremely important for recipients of a diverse ethnic and racial origin to find a compatible match for transplantation purposes.  Carolina Cord Blood Bank released thousands of cord blood units for transplantation purposes worldwide.  This public banking facilityOpens in a new tab. also uses cord blood samples of insufficient qualityOpens in a new tab. for transplant for research and development purposes.  These samples are readily available for clinical studies investigating the new modalities of use of stem cells and their nature and biology.

Carolina Cord Blood Bank Mission

Carolina Cord Blood Bank actively works on building the largest and most diverse inventory of cord blood units for future therapeutic use in patients requiring stem-cell transplantation.Opens in a new tab.  Carolina Cord Blood Bank also invests a lot of effort in training the personnel in order to provide the best quality of service for both the donors and recipients.

Carolina Cord Blood Bank constantly aims to improve the processes of collection,Opens in a new tab. processing, storage, and release of cord blood units with the final goal to improve the health outcomes following stem cell transplantationOpens in a new tab..  This banking system recognizes the importance of investigating and developing new treatment modalities that include the use of stem cellsOpens in a new tab..  Therefore, Carolina Cord Blood Bank actively participates in clinical trials that are focused on finding new therapeutic indicationsOpens in a new tab. for stem cells originating from cord blood.

Collection by Carolina Cord Blood Bank

Carolina Cord Blood Bank developed a collection program consisted of sampling cord blood in several hospitals in the United States or via collection kitOpens in a new tab..  The team of highly skilled professionals works within the hospital and collects cord blood immediately after the baby delivery.  The collection may be also done via the collection kitOpens in a new tab..  The collection processOpens in a new tab. takes less than ten minutes, except complications derived from a nuchal cord caseOpens in a new tab..

The team works closely with the mother during the delivery period in order to obtained an informed consent from the mother to donate the cord blood, obtain the sample of mother’s blood for the purpose of further testing, interview the mother in order to get the information regarding the family medical history and finally collects the cord blood.  The sample may be taken after the vaginal delivery or Caesarean section.  The sampling of umbilical cord bloodOpens in a new tab. may be done after the delivery of the baby while the placenta is still in the uterus or after the delivery of the placenta.

Processing Of Cord Blood

Following the collection process, cord blood unit must be transported within the timeframe of 45 hours to the processing laboratory at the Dukes University.  When the units arrive, they undergo processing that includes checking of the unit identity, testing of the unit, assessment of viability and quality of the collected unit and preparation of cord bloodOpens in a new tab. for further cryopreservation.

We have not been informed by any of the users of Carolina Cord Blood Bank if the bank collects cord tissue apart from cord bloodOpens in a new tab., or if it banks also cord tissueOpens in a new tab. or if it is accredited by AABB.Opens in a new tab. Carolina Cord Blood Bank themselves, did not inform us if they provide cord tissue bankingOpens in a new tab. as well. If you want to store cord tissueOpens in a new tab., you have to go to a private cord blood bankOpens in a new tab. such as StemCyte,Opens in a new tab. Family CordOpens in a new tab., ViaCord,Opens in a new tab. CBR,Opens in a new tab. CryoCellOpens in a new tab. and many more we have reviewedOpens in a new tab., despite their higher costsOpens in a new tab..

Preservation Of Cord Blood

If the samples are assessed as eligible, units undergo the process of cryopreservation that includes the freezing of the units in nitrogen tanks.  The temperature of tanks is constantly being monitored to ensure no temperature fluctuations that might affect unit quality.  Once the unit is cryopreserved, it becomes available at National Marrow Donor Program’s Be the Match® RegistryOpens in a new tab..  This way, physicians may access the database and search for a compatible donor.  The units are cryopreserved for at least twenty years.  The current knowledge from various studies indicates that the units may be cryopreserved even longer, without any effects on the quality of stored stem cells.

Release After Identification Of A Donor

Once a compatible donor has been identified, a tiny part of the unit is being extracted from the whole sample and tested to confirm the identity of the unit as well as the viability of stem cells within the sample.  If the sample is confirmed as a match for transplant and viable, the unit is transported in specific frozen conditions to the site requiring the unit for transplant.  Once the unit reaches the final destination, it undergoes thawing and preparation for the transplant.

Carolina Cord Blood Bank with its affiliates recognizes the importance of unit quality.  Therefore, Carolina Cord Blood Bank has developed and constantly improves the procedures regarding the Quality Control, Regulatory aspects, and Project management with a milestone to reach the highest standards in the field of stem cell bankingOpens in a new tab..


Sandra Eades

Hello I am Sandra Eades, physician, researcher and author from Australia. I am working currently as researcher for a private institution. I have studied in Britain and Australia, where I currently reside. I write about research topics in the organization of the public health government agencies. For the iMS I write about general medical conditions. I also research scholar sources to provide information to writers of other articles. I also check the citations of scholar papers. Finally, I read other articles before they are published. I am also a mother of three children!

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