StemCyte


StemCyte

StemCyte is one of the leading umbilical cord blood banking systems present on the international level, with locations in the USA, India and Taiwan.  SyemCyte represents a combination of a public cord blood banking facility and a private umbilical cord blood bank.

To compare StemCyte with other cord blood banksOpens in a new tab., see our cord blood banking reviews articleOpens in a new tab.. To discover which are the preferred features for a cord blood banking institution, go to this articleOpens in a new tab.. In general, this company does not stand so well when compared with thers such as ViaCord,Opens in a new tab. Americord,Opens in a new tab. or CBR,Opens in a new tab. to name a few.

The milestone of this institution, StemCyte, is to provide a diverse and global umbilical cord blood pool from which both publicOpens in a new tab. and privateOpens in a new tab. users would have therapeutic benefit.  StemCyte has reached the highest diversity of umbilical cord blood units and has provided umbilical cord blood to a significant number of patients worldwide.  Approximately two thousand donated umbilical cord blood unitsOpens in a new tab. were released for therapeutic use from the public bank directly to the hospitals around the world.  A successful merging of private and public cord blood banking allows StemCyte to provide the highest standards in the field of umbilical cord blood collection, storage and release for therapeutic use.

The diversity and an impressive number of umbilical cord blood units stored in the facility give StemCyte the ability to cooperate with leading global experts, and some public cord blood banksOpens in a new tab., and create an Advanced Therapeutics initiative, which resulted in clinical trials investigating the role of cord bloodOpens in a new tab. in the treatment of thalassemia, spinal cord injury, and stroke.  No other company possesses in our cord blood banking reviewsOpens in a new tab. such business model, consisted of three major components: privateOpens in a new tab. and public blood bankingOpens in a new tab. with substantial potential for investigating new modalities of umbilical cord blood use.

 

STEMCYTE BUILDING IN CALIFORNIA. TAKEN BY EMILY SANDOVAL.

Hybrid Model: Public and Private

The key advantage of StemCyte is the conjunction between public and private umbilical cord blood banking, international presence and a vast investigational potential.  This allows StemCyte to cooperate with international experts in the field of umbilical cord blood banking with a final goal to expand the therapeutic use of umbilical cord blood beyond the current approved therapeutic indications.

Research in the field of thalassemia, stroke and spinal injury has provided promising results and opened a path towards the understanding of the umbilical cord blood potentialsOpens in a new tab. and broadening of cord blood therapeutic use.  StemCyte possesses significant experience in releasing the units for therapeutic use on children and adults.  As aforementioned earlier, over 2000 cord blood units were released in order to successfully treat various severe and life-threatening diseases including cancer (leukemia, lymphoma, multiple myeloma), blood disorders (thalassemia, scale cell anemia, Fanconi anemia) and conditions of immune deficiency.

Umbilical Cord Blood Processing by StemCyte

Standard umbilical cord blood processingOpens in a new tab. method eliminates both plasma and red blood cells from the collected sample, leaving the unit volume of approximately 25 mililiters.  This method is most commonly used in UCB processing practice.

StemCyte uses the MaxCell processing method in which only plasma is removed and red blood cells left in the final sample.  This modality has shown to provide a higher number of Total Nucleated Cells (TNC).  The total nucleated cell number is directly proportional to the number of stem cells in the collected sample, meaning that MaxCell processing method ensures an increased number of stem cells per sample when compared with standard processing methodology.

Accreditations for StemCyte

FDA registered

Food and Drug Administration (FDA) has recognized the high operational standards of StemCyte including the HLA typing laboratory that provides prompt tissue typing when an urgent transplant is needed within the hospital setting.

Foundation for the Accreditation of Cellular Therapy (FACT)

FACT believes that high quality of services encompasses a clinical aspect of cord blood banking, as well as laboratory aspect that includes processing and storage of UCB units.  In order to receive a valid accreditation, both aspects of cord blood banking have to be evaluated and approved.

StemCyte was the first cord blood institution to receive FACT approval and recognition in all three activities including unrelated and related allogenic transplantation and autologous stem cell transplantation.  StemCyte met all the criteria for cord blood banking – sampling, handling, testing, storing, selecting and releasing of units for transplant.  The prestigious FACT award was received in 2006.  StemCyte is the only institution approved by FACT for autologous transplantation. This information is updated at the end of 2018.

AABB Accredited

AABBOpens in a new tab. is well recognized by its internationally accepted standards in the fields of blood banking, transfusion and cellular therapy laboratories including cord blood banking facilities.  StemCyte initially received accreditation from this institution in 2002 under the AABB standards for cord blood management and banking.  Currently, StemCyte is accredited by AABB under the 1st edition of the Standards for Cellular Therapy Services.

LifeSaver Guarantee

StemCyte implemented a new level of added security to cord blood banking.  If the stem cells were not engrafted following transplantation procedure, StemCyte was refunding all the fees paid for banking services including an additional reimbursement. Currently StemCyte is not doing this anymore, so there is a disadvantage in comparison with its competitorsOpens in a new tab. that offer reimbursementsOpens in a new tab. and compensations.Opens in a new tab.

Another practice abandoned by StemCyte was the following: a search for another compatible cord blood unit was conducted, and if an acceptable HLA match was available, the unit was released for transplant.  In the situation when the collecting unit iwas being damaged by transport, processing or storage and if the family decided to stay enrolled in the program, StemCyte was also conducting a search for compatible alternative cord blood product and releasing it for transplantation for a child or a family member, if required.

Stable Temperature Collection Kit

Maintenance of the stable temperature of the umbilical cord blood sample throughout the transport is essential for the viability of stem cells.  Better protection from temperature oscillations ensures the safety of collected stem cells.  StemCyte uses the thermally insulated collection kitOpens in a new tab. that maintains the optimal temperature of cord blood sample during transport.  This is one of the very few kits in the industry, but not the only oneOpens in a new tab., that ensure a stable temperature of cord blood.

The collection kitOpens in a new tab. is heavily insulated and tested for thermal-protection in various outer temperatures.  Collection kit meets all the regulatory requirements for successful collection and transport of umbilical cord bloodOpens in a new tab. and has undergone clinical trials to meet the recommendations provided by the FDA.  The kit allows both cord blood and cord tissueOpens in a new tab. to be collected.

Research done by StemCyte

In 2007, StemCyte in collaboration with Prof. Wise Young submitted a patent application for the combination of cord blood and lithium that was noted to promote the secretion of several neurotropic agents responsible for stimulating the body’s own stem cells leading to growth and repair of nervous tissue.

In 2008, StemCyte introduced a new patent using umbilical cord blood stem cells to treat brain damage caused by stroke or traumatic brain injury.  StemCyte also worked on a specific method that would enable the cord blood stem cellsOpens in a new tab. to be resistant to HIV infection.

In 2010, a Phase II clinical trial that investigated the use of UCB stem cells in the treatment of chronic stroke was completed.  The results demonstrated a success rate of approximately 85%.  Spinal cord injury and the treatment of this condition using stem cell transplantation was also investigated in Phase I/II clinical trial sponsored by StemCyte.  The development of regenerative medicine was also highly influenced by StemCyte back in 2013 when a program was launched to investigate the therapeutic potential of mesenchymal and epithelial cells.  The goal of this program was to expand the therapeutic use of umbilical cord blood by storing the aforementioned cell typesOpens in a new tab..  When the therapeutic potential of these cells was recognized by the experts, around 600 clinical trials were launched with the objective to investigate the use of mesenchymal stem cells in the treatment of heart disease, autoimmune disorders, diabetes, liver and kidney diseases.

 

Sandra Eades

Hello I am Sandra Eades, physician, researcher and author from Australia. I am working currently as researcher for a private institution. I have studied in Britain and Australia, where I currently reside. I write about research topics in the organization of the public health government agencies. For the iMS I write about general medical conditions. I also research scholar sources to provide information to writers of other articles. I also check the citations of scholar papers. Finally, I read other articles before they are published. I am also a mother of three children!

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