{"id":496,"date":"2018-01-01T23:34:19","date_gmt":"2018-01-01T23:34:19","guid":{"rendered":"https:\/\/mesotheliomacommunity.com\/?p=496"},"modified":"2018-01-01T23:34:19","modified_gmt":"2018-01-01T23:34:19","slug":"epithelioid-mesothelioma","status":"publish","type":"post","link":"https:\/\/imedicalsociety.org\/epithelioid-mesothelioma\/","title":{"rendered":"Epithelioid Mesothelioma"},"content":{"rendered":"
Epithelioid mesothelioma is generally a disease of older adults with more than 90% of cases being diagnosed after the age of 50<\/a>. Epithelioid mesothelioma has one of the best prognosis<\/a>, and most of the chemotherapeutic drugs work well against this type of cancer. Here we will see how.<\/p>\n Mesothelioma is divided into three categories according to cell types. These three types are epithelioid, sarcomatoid,<\/a> or biphasic.<\/a><\/p>\n Cell type of mesothelioma is decided after examination of the cancer tissue under the microscope<\/a>, that is through histological examination. It is vital to find out the cell type, as the prognosis of mesothelioma<\/a> is highly dependent on it. With that procedure is how we arrive to recognize epithelioid mesothelioma.<\/p>\n Among all the cell types epithelioid is the most common form that is found in about 60-70% of all the cases. Cells in epithelioid mesothelioma have a specific elongated pattern<\/a> that is easily distinguishable under the microscope.<\/p>\n Epithelioid Mesothelioma has to be differentiated from another common cancer<\/a> of the lungs called adenocarcinoma. The problem in differentiation arises due to the fact that both epithelioid mesothelioma and adenocarcinoma emerge from the so-called epithelium cells. Epithelium cells are very common in our body, lining all the mucus-producing body linings.<\/p>\n It is vital to differentiate between epithelioid mesothelioma and adenocarcinoma as they have entirely different treatment protocols<\/a>. Fortunately, researchers have come up with lots of newer stains for making this differentiation activity easier, like immunochemistry, described below.<\/p>\n So here is where immunochemistry comes into the scenario to facilitate the diagnosis<\/a> of epithelioid mesothelioma.<\/p>\n Traditionally, electron microscopy and staining of hyaluronic acid have been used. However, nowadays immunochemistry markers are the more precise method of differential diagnosis<\/a>. But things are not that simple as no single immunohistochemical marker may confirm the diagnosis of the particular type of cancer<\/a>. Mesothelin, calretinin, or cytokeratin 5\/6 some of the commonly used immune markers.<\/p>\nDifferential Diagnosis Of Epithelioid Mesothelioma<\/span><\/strong><\/h1>\n
Immunochemistry For Accurate Differentiation And Recognition Of Epithelioid Mesothelioma<\/strong><\/h2>\n